Arun research focusses on the development of computational methods and tools to study the structural and functional relationship of biological macromolecules with specific focus on molecular recognition, analysis of protein-ligand interactions, ab initio protein structure prediction, modelling atomic models into cryo electron microscopy maps, predicting the effects of disease causing mutations on the protein stability and interactions and annotation of genomes using protein structural information.
Arun Prasad Pandurangan is an Investigator Scientist at the MRC Laboratory of Molecular Biology, Cambridge. He has been a Research Associate and an Honorary Teaching Associate at the department of Biochemistry, University of Cambridge (2015-2016). Previously, he worked as a Research Associate at Birkbeck College, University of London (2009-2015).
Arun Prasad Pandurangan research interest focuses on the development of computational tools to predict protein structures and ligand-receptor complexes; elucidate biological function by fitting, refining and validating atomic models into cryo-EM density maps; predict the effects of mutations on protein stability and interaction; analysis of infectious and drug resistant mutations and genome annotation.
Currently, he is investigating the problem of annotating genome and proteome sequences with three dimensional structures of known protein domains for the purpose of elucidating the relationship between protein sequence, structure, disorder, function and dynamics.
Arun Prasad Pandurangan has volunteered as a Science Communicator in various public events including the Cambridge Science Festival (2016-2017), 'Ask a biologist' at New Scientist Live 2016, Cambridge Big Week 2018 and the Sidney Sussex College Open Day 2019. He is a Member and an Ambassador of the Royal Society of Biology as well an active STEM Ambassador.