College Fellows and Staff

Dr Meisl

Dr Georg Meisl

Research Fellow in Natural Sciences (Chemistry)

Email: gm373@cam.ac.uk

Web: Department

Personal Biography

Georg Meisl completed his undergraduate studies in Natural Sciences at Cambridge and MIT, then obtained a PhD in Biophysical Chemistry at Cambridge. His main research interest is in biological and biophysical phenomena related to protein aggregation, such as the key processes involved in Alzheimer's and Parkinson's diseases. A particular focus of his work is to develop fundamental theoretical models and apply them in the analysis of biologically relevant experimental data.

Selected Publications

• Andela Šaric, G Meisl, AK Buell, TCT Michaels, S Linse, TPJ Knowles and D Frenkel, “Physical determinants for the self-replication of protein fibrils”, Nature Physics 12, 874–880 (2016)

• G Meisl, JB Kirkegaard, P Arosio, M Vendruscolo, CM Dobson, S Linse and TPJ Knowles, “Molecular mechanisms of protein aggregation from global fitting of kinetic models”, Nature Protocols 11, 252 (2016)

• G Meisl, X Yang, B Frohm, TPJ Knowles and S Linse “Quantitative analysis of intrinsic and extrinsic factors in the aggregation mechanism of Alzheimer-associated Aβ-peptide”, Scientific reports 6, 18728 (2016)

• G Meisl, X Yang, E Hellstrand, B Frohm, JB Kirkegaard, SIA Cohen, CM Dobson, S Linse and TPJ Knowles, "Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides.", PNAS, 111, 9384 (2014)